Immunomodulatory Effects of Flumequine and Enrofloxacin on Newcastle Disease Virus Vaccinated Broiler Chicks

Immunomodulatory effects of Flumequine and enrofloxacin were evaluated on humoral immune response of Newcastle disease virus (NDV) vaccinated broiler birds. It was observed that birds receiving flumequine as growth promoter had higher mean body weights, better feed conversion ratio, higher NDV haemagglutination inhibition (HI) antibody, lesser overall mortality, 100% protection against challenge with virulent NDV and no detrimental effects on their lymphoid organs compared to the cyclophosphamide treated and untreated chicks. It was concluded that the use of flumequine has good effect on growth and performance of the treated chicks. However enrofloxacin treatment of chicks as growth promoter does not have effects comparable to flumequine. The cyclophosphamide treatment adversely affected the performance of chicks.